In this clip from the Magic Sandwich Show, dprjones and AronRa are speaking with Matt Dillahunty of The Atheist Experience. Starting at 11:54, Matt describes what he considers to be the best approach for atheists to take when dealing with the religious:

I think there is a best way, and the best way, despite the negative reaction you will often get, is confrontation. Now that doesn’t necessarily mean hostility. But I have yet to meet somebody who’s changed their mind on something without being confronted by a direct opposition. That doesn’t mean you have to be necessarily in your face or, you know, yelling or anything like that.

But if you don’t challenge them – and that is, ‘Okay, what evidence have you got? Can you provide that evidence?’ – if you don’t put something forward, you might as well not even have the conversation. Because, it reminds me of the, ‘Uh, well, let’s just agree to disagree.’ You know, fuck that. We already knew we disagreed before we started the conversation. Why would you end it that way? That makes no sense to me.

I couldn’t agree more.

I should also mention that this was part of the Doctors Without Borders Charity organized by dprjones, and that the donations pages are still open here and here (these links can also be found in the video description).